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Two Examples of Mice Experiments - Valid or Not?

Critter News

I came across these stories about two different medical experiments using mice. They used different lighting situations to see how they affect mice moods. Plus, are mice comparable to kids (although I would prefer mice subjects to primates who are so much more sensitive)? One of the conclusions?

Mice 100
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Growing Number of Scientists Question Animal Research

Critter News

They're not necessarily questioning the ethics, but the efficacy. The feud between animal rights activists and researchers is among the bitterest in science. Indeed, it often isn't even the best science: New drugs that show great promise in mice, for example, often confer zero benefit to humans, or even prove harmful.

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Deconstructing Slate's "Pepper" Series

Animal Person

There's a vague sense that perhaps he cares about the dogs or thinks that what he does to them might present an ethical dilemma, but the overwhelming feeling is that it's all worth it. He concludes this segment with: Meanwhile, rats and mice are subject to some of the most extreme and invasive experiments in biomedicine.